L3MBTL4

Across TCGA patient cohorts, L3MBTL4 protein abundance is significantly associated with the RNA expression of many other genes, with 756 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible L3MBTL4-associated genes across cancer lineages are CEMIP, USP9Y, and FGF23. Each is linked with L3MBTL4 in more than 1 cancer types. Because this analysis shows association rather than direction, both L3MBTL4-to-partner and partner-to-L3MBTL4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, L3MBTL4 versus CEMIP in LUAD, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (L3MBTL4→partner) and Y-score (partner→L3MBTL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CEMIP →	-1.408	-0.859	.003	.003	3	1
LUAD	USP9Y →	-2.795	-0.955	.001	.006	3	1
LUAD	FGF23 →	-0.066	-0.872	.008	.008	3	1
LUAD	PTGIS →	-0.941	-1.052	<.001	<.001	3	1
LUAD	KDM5D →	-2.702	-0.919	.001	.004	3	1
LUAD	MPST →	-0.528	-1.182	.006	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 756 associations by consensus.

L3MBTL4 vs CEMIP — LUAD

Explore this scatter interactively →