Across TCGA cell cohorts, L3MBTL3 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible L3MBTL3-associated genes across cancer lineages are ITGAD, C3orf22, and OR4F15. Each is linked with L3MBTL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both L3MBTL3-to-partner and partner-to-L3MBTL3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (L3MBTL3→partner) and Y-score (partner→L3MBTL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ITGAD →	+0.009	+3.247	.001	.001	3	2
URINARY_TRACT	C3orf22 →	+0.016	+4.584	<.001	.002	3	1
URINARY_TRACT	OR4F15 →	+0.138	+4.217	<.001	.005	3	1
URINARY_TRACT	DCDC2C →	+0.126	+4.217	<.001	.005	3	1
URINARY_TRACT	GH1 →	+0.067	+4.584	<.001	.002	3	1
URINARY_TRACT	OTC →	+0.031	+4.217	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

Exploration

L3MBTL3 survival (RNA) · tumor vs normal (RNA) · all L3MBTL3 data types