Across TCGA patient cohorts, L3MBTL1 mutation is significantly associated with the RNA expression of many other genes, with 3,055 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible L3MBTL1-associated genes across cancer lineages are UHRF1, THAP7, and ISCA1P4. Each is linked with L3MBTL1 in more than 3 cancer types. Because this analysis shows association rather than direction, both L3MBTL1-to-partner and partner-to-L3MBTL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (L3MBTL1→partner) and Y-score (partner→L3MBTL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	UHRF1 →	+0.858	+2.126	<.001	<.001	3	3
COAD	THAP7 →	+0.443	+3.713	.001	<.001	3	3
COAD	ISCA1P4 →	+0.861	+3.713	<.001	<.001	3	3
COAD	CENPU →	+0.765	+3.348	.001	.004	3	3
COAD	CXXC1 →	+0.558	+3.754	<.001	<.001	3	3
UCEC	MELK →	+0.538	+2.332	.008	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,055 associations by consensus.

Exploration

L3MBTL1 survival (RNA) · tumor vs normal (RNA) · all L3MBTL1 data types