Across TCGA cell cohorts, L3MBTL1 mutation is significantly associated with the RNA expression of many other genes, with 49 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible L3MBTL1-associated genes across cancer lineages are OR1N2, GZMK, and OOSP2. Each is linked with L3MBTL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both L3MBTL1-to-partner and partner-to-L3MBTL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (L3MBTL1→partner) and Y-score (partner→L3MBTL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR1N2 →	+0.025	+5.029	<.001	.006	3	2
BREAST	GZMK →	+0.056	+5.169	<.001	.005	3	1
BREAST	OOSP2 →	+0.023	+5.781	<.001	.001	3	1
BREAST	OR10J5 →	+0.071	+5.169	<.001	.005	3	1
BREAST	OR10J1 →	+0.566	+5.781	<.001	.001	3	1
SKIN	OR5B17 →	+0.026	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

Exploration

L3MBTL1 survival (RNA) · tumor vs normal (RNA) · all L3MBTL1 data types