KYAT3

Across TCGA patient cohorts, KYAT3 mutation is significantly associated with the RNA expression of many other genes, with 2,131 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KYAT3-associated genes across cancer lineages are TIMM9P3, RNA5SP411, and SNORD114-1. Each is linked with KYAT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KYAT3-to-partner and partner-to-KYAT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TIMM9P3 grouped by KYAT3-low versus KYAT3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KYAT3→partner) and Y-score (partner→KYAT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TIMM9P3 →	+0.132	+4.495	<.001	.007	3	2
UCEC	RNA5SP411 →	+1.393	+2.256	<.001	<.001	3	2
HNSC	SNORD114-1 →	+0.565	+5.124	<.001	.008	3	2
BRCA	OR7E103P →	+0.098	+5.721	<.001	.003	3	2
BRCA	RNU6-1022P →	+0.239	+8.057	<.001	.005	3	2
BRCA	RNU6ATAC11P →	+0.331	+5.096	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,131 associations by consensus.

TIMM9P3 by KYAT3 expression — SKCM

Explore this box plot interactively →