KYAT3

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KYAT3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,566 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible KYAT3-associated GO terms across cancer lineages are Zinc ion import into Golgi lumen, Positive regulation of centriole replication, and L-kynurenine catabolic process. Each is linked with KYAT3 in more than 10 cancer types. Because this analysis shows association rather than direction, both KYAT3-to-partner and partner-to-KYAT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Zinc ion import into Golgi lumen grouped by KYAT3-low versus KYAT3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KYAT3→partner) and Y-score (partner→KYAT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUSCZinc ion import into Golgi lumen →+0.088+0.833.001.003311
UPPER_AERODIGESTIVE_TRACTPositive regulation of centriole replication →+0.134+1.037<.001<.00139
BONEL-kynurenine catabolic process →+0.982+1.271.004.00239
UPPER_AERODIGESTIVE_TRACTCD40 signaling pathway →-0.120-0.714<.001.00138
UPPER_AERODIGESTIVE_TRACTRegulation of centriole replication →+0.076+0.894.002.00338
URINARY_TRACTProtein acetylation →+0.062+0.945.001.00829
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,566 associations by consensus.

Zinc ion import into Golgi lumen by KYAT3 expression — LUNG_NSCLC_LUSC

Box plot of Zinc ion import into Golgi lumen in KYAT3-low vs KYAT3-high samples in LUNG_NSCLC_LUSC.

Explore this box plot interactively →

Exploration