KYAT3

Across TCGA cell cohorts, KYAT3 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KYAT3-associated genes across cancer lineages are ST6GAL2, TKTL2, and TAFA1. Each is linked with KYAT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KYAT3-to-partner and partner-to-KYAT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ST6GAL2 grouped by KYAT3-low versus KYAT3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KYAT3→partner) and Y-score (partner→KYAT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ST6GAL2 →	+0.915	+3.839	<.001	.001	3	1
LARGE_INTESTINE	TKTL2 →	+0.044	+3.509	<.001	.001	3	1
LARGE_INTESTINE	TAFA1 →	+0.205	+2.688	.004	.008	3	1
LARGE_INTESTINE	CHSY3 →	+0.556	+3.252	<.001	.009	3	1
LARGE_INTESTINE	BPIFA1 →	+0.098	+2.688	.008	.008	3	1
LARGE_INTESTINE	FAM205A →	+0.023	+3.029	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

ST6GAL2 by KYAT3 expression — LARGE_INTESTINE

Explore this box plot interactively →