KTN1

Across TCGA pan-cancer cohorts, KTN1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated KTN1 data layer compared with 25 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher KTN1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated KTN1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and PDAC show a favorable association.

UCEC, LUAD, and LSCC are the cancer types where KTN1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Quartile	II,III,IV	1.000	0.338	.022	24	view →
LUAD	DFS	Tertile	All	0.897	0.960	.007	23	view →
LSCC	DFS	Median	All	0.616	0.799	.022	10	view →
PDAC	OS	Median	II,III,IV	0.935	0.729	.024	3	view →
CCRCC	OS	Tertile	All	0.936	0.764	.018	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

KTN1–UCEC (OS)

Open the UCEC breakdown →