Across TCGA pan-cancer cohorts, KTI12 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated KTI12 data layer compared with 24 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher KTI12 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated KTI12 expression acts as an unfavorable survival marker.

READ and HNSC are the cancer types where KTI12 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	DFS	Median	All	0.082	0.845	<.001	18	view →
HNSC	OS	Median	All	0.167	0.710	.005	17	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: KTI12 tumor-vs-normal RNA expression · all KTI12 data types