KTI12

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KTI12 mutation is significantly associated with the RNA expression of many other genes, with 558 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KTI12-associated genes across cancer lineages are LINC00428, RN7SL393P, and MIR548AV. Each is linked with KTI12 in more than 1 cancer types. Because this analysis shows association rather than direction, both KTI12-to-partner and partner-to-KTI12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KTI12→partner) and Y-score (partner→KTI12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCLINC00428 →+0.191+5.306<.001.00632
HNSCRN7SL393P →+0.796+4.685<.001.00132
BLCAMIR548AV →+0.397+7.640<.001.00932
UCECVN1R91P →+0.254+3.036<.001.00932
COADPRYP2 →+0.219+7.741<.001.00932
CESCARF4P3 →+0.079+5.010.006.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 558 associations by consensus.

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