Across TCGA patient cohorts, KTI12 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KTI12-associated genes across cancer lineages are PCNA, AR, and Lck. Each is linked with KTI12 in more than 1 cancer types. Because this analysis shows association rather than direction, both KTI12-to-partner and partner-to-KTI12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KTI12→partner) and Y-score (partner→KTI12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.353	+3.169	.002	.019	3	1
UCEC	AR →	-0.549	-3.169	.007	.020	2	1
UCEC	Lck →	+0.271	+3.169	.014	.020	1	1
UCEC	Annexin-1 →	+0.768	+3.169	.007	.020	1	1
UCEC	TFRC →	+0.704	+3.169	.015	.020	1	1
UCEC	Caspase-7-cleavedD198 →	+1.259	+3.169	<.001	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

KTI12 survival (RNA) · tumor vs normal (RNA) · all KTI12 data types