Across TCGA cell cohorts, KTI12 mutation is significantly associated with the mutation status of many other genes, with 600 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KTI12-associated genes across cancer lineages are RIOK3, ZNF200, and TUBA3D. Each is linked with KTI12 in more than 1 cancer types. Because this analysis shows association rather than direction, both KTI12-to-partner and partner-to-KTI12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KTI12→partner) and Y-score (partner→KTI12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	RIOK3 →	+4.309	+4.560	.007	.007	1	2
BLOOD_Leukemia	ZNF200 →	+4.309	+4.560	.007	.007	1	2
BLOOD_Leukemia	TUBA3D →	+4.894	+4.894	.004	.004	1	2
BLOOD_Leukemia	IGBP1 →	+4.894	+4.894	.004	.004	1	2
BLOOD_Leukemia	ASB16 →	+4.479	+5.635	<.001	<.001	1	2
BLOOD_Leukemia	CGAS →	+4.894	+5.870	<.001	<.001	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 600 associations by consensus.

Exploration

KTI12 survival (RNA) · tumor vs normal (RNA) · all KTI12 data types