KSR2

Across TCGA patient cohorts, KSR2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,827 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KSR2-associated genes across cancer lineages are DPP4, PEA15, and AGPAT3. Each is linked with KSR2 in more than 3 cancer types. Because this analysis shows association rather than direction, both KSR2-to-partner and partner-to-KSR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KSR2 versus DPP4 in LUAD, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KSR2→partner) and Y-score (partner→KSR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	DPP4 →	+1.326	+0.478	<.001	.001	3	4
GBM	PEA15 →	+0.648	+0.534	<.001	<.001	3	3
LSCC	AGPAT3 →	+0.308	+0.416	<.001	.007	3	3
BRCA	CHD8 →	+0.363	+0.951	.009	.009	3	2
LSCC	RRN3P2 →	+0.232	+0.551	.003	.006	3	2
BRCA	PIAS4 →	+0.594	+1.145	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,827 associations by consensus.

KSR2 vs DPP4 — LUAD

Explore this scatter interactively →