KSR1

Across TCGA patient cohorts, KSR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,900 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KSR1-associated proteins across cancer lineages are KSR1_S406, KSR1_T425, and KSR1_S547. Each is linked with KSR1 in more than 6 cancer types. Because this analysis shows association rather than direction, both KSR1-to-partner and partner-to-KSR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KSR1 versus KSR1_S406 in BRCA, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KSR1→partner) and Y-score (partner→KSR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KSR1_S406 →	+0.492	+0.633	<.001	<.001	3	7
LUAD	KSR1_T425 →	+2.192	+1.366	<.001	<.001	3	5
LUAD	KSR1_S547 →	+0.681	+0.895	<.001	<.001	3	5
BRCA	KSR1_S311 →	+2.050	+1.438	<.001	<.001	3	5
PDAC	SH3BGRL3 →	-0.479	-0.456	.004	.001	3	4
LUAD	CACNA2D2 →	+0.729	+0.903	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,900 associations by consensus.

KSR1 vs KSR1_S406 — BRCA

Explore this scatter interactively →