KSR1

Across TCGA cell cohorts, KSR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,094 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible KSR1-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Regulation of myoblast fusion, and Negative regulation of myoblast fusion. Each is linked with KSR1 in more than 14 cancer types. Because this analysis shows association rather than direction, both KSR1-to-partner and partner-to-KSR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by KSR1-low versus KSR1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KSR1→partner) and Y-score (partner→KSR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.193	+2.126	<.001	<.001	3	15
OESOPHAGUS	Regulation of myoblast fusion →	+0.173	+2.126	<.001	<.001	3	13
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.116	+1.652	<.001	<.001	3	13
OESOPHAGUS	Cytoplasmic translation →	+0.142	+2.033	<.001	<.001	3	13
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.143	+1.953	<.001	<.001	3	13
OESOPHAGUS	mRNA transport →	+0.121	+1.561	.003	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,094 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by KSR1 expression — OESOPHAGUS

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