KRTCAP2P1

Across TCGA pan-cancer cohorts, KRTCAP2P1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of KRTCAP2P1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where KRTCAP2P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KRTCAP2P1 is over-expressed in tumor, although a few such as KICH and STAD show the opposite, repressed pattern.

COAD, LIHC, and BRCA are the cancer types where KRTCAP2P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KRTCAP2P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	+1.541	<.001	9	view →
LIHC	Male	All	+0.218	<.001	7	view →
BRCA	All	II,III,IV	+0.179	<.001	6	view →
LUAD	All	All	+0.159	<.001	5	view →
UCEC	All	All	+0.739	.030	4	view →
KICH	All	II,III,IV	−0.200	.026	3	view →
LUSC	All	All	+0.149	.002	3	view →
KIRP	All	All	+0.085	.026	2	view →
ESCA	Male	All	+0.585	.033	1	view →
STAD	All	III,IV	−0.356	.048	1	view →
KIRC	Female	III,IV	+0.143	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

KRTCAP2P1–COAD

Open the COAD breakdown →