Across TCGA patient cohorts, KRTAP9-9 mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP9-9-associated genes across cancer lineages are ACC_pS79, Notch1, and p38-MAPK. Each is linked with KRTAP9-9 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP9-9-to-partner and partner-to-KRTAP9-9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP9-9→partner) and Y-score (partner→KRTAP9-9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACC_pS79 →	+0.560	+2.817	.002	.036	3	1
UCEC	Notch1 →	+0.187	+2.817	.011	.036	3	1
UCEC	p38-MAPK →	-0.172	-3.321	.046	.010	3	1
UCEC	EGFR_pY1068 →	-0.331	-3.321	.011	.010	2	1
UCEC	ACC1 →	+0.584	+3.321	.002	.010	2	1
UCEC	p38-MAPK_pT180_Y182 →	-0.548	-3.308	.020	.010	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

KRTAP9-9 survival (RNA) · tumor vs normal (RNA) · all KRTAP9-9 data types