KRTAP9-2

Across TCGA patient cohorts, KRTAP9-2 mutation is significantly associated with the RNA expression of many other genes, with 72 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP9-2-associated genes across cancer lineages are MIR4529, RNU6-971P, and RNU6-1260P. Each is linked with KRTAP9-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP9-2-to-partner and partner-to-KRTAP9-2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4529 grouped by KRTAP9-2-low versus KRTAP9-2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP9-2→partner) and Y-score (partner→KRTAP9-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4529 →	+0.348	+4.464	<.001	.005	3	2
UCEC	RNU6-971P →	+0.229	+4.292	<.001	.006	3	2
SKCM	RNU6-1260P →	+0.595	+5.097	<.001	.008	3	1
SKCM	SNORD114-10 →	+0.590	+5.224	<.001	.007	3	1
SKCM	RNU6-645P →	+0.446	+4.979	<.001	.009	3	1
SKCM	RNU6-952P →	+0.417	+6.328	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 72 associations by consensus.

MIR4529 by KRTAP9-2 expression — UCEC

Explore this box plot interactively →