Across TCGA patient cohorts, KRTAP6-3 mutation is significantly associated with the RNA expression of many other genes, with 383 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP6-3-associated genes across cancer lineages are FTCD-AS1, KRTAP12-6P, and MOCS1P1. Each is linked with KRTAP6-3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP6-3-to-partner and partner-to-KRTAP6-3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP6-3→partner) and Y-score (partner→KRTAP6-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FTCD-AS1 →	+0.208	+3.213	.003	.005	3	2
LUSC	KRTAP12-6P →	+0.175	+5.882	<.001	.002	3	2
UCEC	MOCS1P1 →	+0.086	+2.443	.009	.005	3	2
COAD	TRGV11 →	+0.066	+4.962	.006	.003	3	1
COAD	MTCO3P5 →	+0.237	+3.754	<.001	.008	3	1
COAD	MTND3P9 →	+0.251	+4.807	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 383 associations by consensus.

Exploration

KRTAP6-3 survival (RNA) · tumor vs normal (RNA) · all KRTAP6-3 data types