Across TCGA patient cohorts, KRTAP6-1 mutation is significantly associated with the RNA expression of many other genes, with 60 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible KRTAP6-1-associated genes across cancer lineages are RNA5SP358, RPS27P20, and RNU6-1110P. Each is linked with KRTAP6-1 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRTAP6-1-to-partner and partner-to-KRTAP6-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP6-1→partner) and Y-score (partner→KRTAP6-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNA5SP358 →	+0.303	+4.399	<.001	.008	3	3
SKCM	RPS27P20 →	+0.190	+4.531	.003	.005	3	2
LUSC	RNU6-1110P →	+0.534	+3.329	.008	.008	3	2
SKCM	MIR6859-3 →	+0.455	+5.080	<.001	.004	3	1
LUAD	LINC01699 →	+0.167	+4.037	.008	.004	3	1
LUAD	RNU6-666P →	+0.218	+4.730	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 60 associations by consensus.

Exploration

KRTAP6-1 survival (RNA) · tumor vs normal (RNA) · all KRTAP6-1 data types