KRTAP5-3

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KRTAP5-3 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible KRTAP5-3-associated genes across cancer lineages are Myocytes, Th2 cells, and Class-switched memory B-cells. Each is linked with KRTAP5-3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP5-3-to-partner and partner-to-KRTAP5-3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP5-3→partner) and Y-score (partner→KRTAP5-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMMyocytes →+0.044+2.031.006.01831
LUADTh2 cells →+0.319+2.819.001.03631
SKCMClass-switched memory B-cells →-0.043-3.005.029.02621
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

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