Across TCGA cell cohorts, KRTAP5-1 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible KRTAP5-1-associated genes across cancer lineages are CST9L, USP29, and CABS1. Each is linked with KRTAP5-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP5-1-to-partner and partner-to-KRTAP5-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP5-1→partner) and Y-score (partner→KRTAP5-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CST9L →	+0.018	+4.977	<.001	.007	3	1
LUNG_NSCLC_LUAD	USP29 →	+0.016	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	CABS1 →	+0.019	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	RNASE9 →	+0.022	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	PRAMEF14 →	+0.012	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	KRTAP10-3 →	+0.032	+5.228	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

KRTAP5-1 survival (RNA) · tumor vs normal (RNA) · all KRTAP5-1 data types