Across TCGA pan-cancer cohorts, KRTAP4-9 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated KRTAP4-9 data layer compared with 15 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher KRTAP4-9 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated KRTAP4-9 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

COAD and SKCM are the cancer types where KRTAP4-9 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	III,IV	0.056	0.783	<.001	18	view →
SKCM	OS	Median	All	1.000	0.333	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: KRTAP4-9 tumor-vs-normal RNA expression · all KRTAP4-9 data types