Across TCGA patient cohorts, KRTAP4-9 mutation is significantly associated with the RNA expression of many other genes, with 627 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP4-9-associated genes across cancer lineages are RNU6-1060P, MCUR1P2, and RNU6-597P. Each is linked with KRTAP4-9 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP4-9-to-partner and partner-to-KRTAP4-9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP4-9→partner) and Y-score (partner→KRTAP4-9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-1060P →	+0.456	+4.554	<.001	.009	3	2
BRCA	MCUR1P2 →	+0.148	+7.731	<.001	.009	3	2
SKCM	RNU6-597P →	+0.241	+4.265	<.001	.001	3	2
SKCM	NDUFB4P5 →	+0.052	+4.147	<.001	.008	3	2
GBM	PRPF19P1 →	+0.081	+5.352	<.001	.005	3	1
GBM	MIR7854 →	+0.770	+4.969	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 627 associations by consensus.

Exploration

KRTAP4-9 survival (RNA) · tumor vs normal (RNA) · all KRTAP4-9 data types