KRTAP4-7

Across TCGA pan-cancer cohorts, KRTAP4-7 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated KRTAP4-7 data layer compared with 11 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher KRTAP4-7 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated KRTAP4-7 expression acts as an unfavorable survival marker.

UCEC, LIHC, and SARC are the cancer types where KRTAP4-7 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	III,IV	0.061	0.588	.018	18	view →
LIHC	DFS	Median	All	0.104	0.555	.003	9	view →
SARC	DFS	Median	All	0.101	0.632	.011	6	view →
SCLC	DFS	Median	All	0.192	0.793	.017	6	view →
ESCA	OS	Median	III,IV	0.136	0.573	.023	6	view →
SKCM	DFS	Median	IV	0.040	0.454	.028	6	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

KRTAP4-7–UCEC (OS)

Open the UCEC breakdown →