Across TCGA patient cohorts, KRTAP4-5 mutation is significantly associated with the RNA expression of many other genes, with 120 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP4-5-associated genes across cancer lineages are MRPL57P6, NDUFB5P1, and RN7SKP256. Each is linked with KRTAP4-5 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP4-5-to-partner and partner-to-KRTAP4-5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP4-5→partner) and Y-score (partner→KRTAP4-5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MRPL57P6 →	+0.199	+7.930	<.001	.008	3	2
UCEC	NDUFB5P1 →	+0.281	+3.097	<.001	.004	3	2
UCEC	RN7SKP256 →	+0.271	+3.358	<.001	.006	3	2
LUAD	RNU6-72P →	+0.178	+7.930	<.001	.008	3	1
LUAD	PRAMEF27 →	+0.009	+7.930	<.001	.008	3	1
SKCM	RNU6-1150P →	+0.393	+5.436	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 120 associations by consensus.

Exploration

KRTAP4-5 survival (RNA) · tumor vs normal (RNA) · all KRTAP4-5 data types