KRTAP4-5

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KRTAP4-5 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP4-5-associated genes across cancer lineages are VEGFR2 and cIAP. Each is linked with KRTAP4-5 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP4-5-to-partner and partner-to-KRTAP4-5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP4-5→partner) and Y-score (partner→KRTAP4-5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECVEGFR2 →+0.423+2.820.020.03631
UCECcIAP →+0.195+2.833.020.03531
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

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