Across TCGA pan-cancer cohorts, KRTAP4-3 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated KRTAP4-3 data layer compared with 11 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher KRTAP4-3 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated KRTAP4-3 expression acts as an unfavorable survival marker.

ACC are the cancer types where KRTAP4-3 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.195	0.748	.003	3	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: KRTAP4-3 tumor-vs-normal RNA expression · all KRTAP4-3 data types