Across TCGA cell cohorts, KRTAP27-1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible KRTAP27-1-associated genes across cancer lineages are APOL5, ACTL9, and CASP12. Each is linked with KRTAP27-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP27-1-to-partner and partner-to-KRTAP27-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP27-1→partner) and Y-score (partner→KRTAP27-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	APOL5 →	+0.106	+4.930	<.001	.001	3	1
SKIN	ACTL9 →	+0.025	+5.022	<.001	.002	3	1
SKIN	CASP12 →	+0.034	+4.095	.009	.009	3	1
LARGE_INTESTINE	OR2D3 →	+0.030	+4.095	<.001	.009	3	1
SKIN	PAPOLB →	+0.081	+4.044	<.001	.009	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

KRTAP27-1 survival (RNA) · tumor vs normal (RNA) · all KRTAP27-1 data types