KRTAP25-1

Across TCGA pan-cancer cohorts, KRTAP25-1 RNA is linked to patient survival in 3 of 34 cancer types, making it the most broadly survival-associated KRTAP25-1 data layer compared with 2 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher KRTAP25-1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KRTAP25-1 expression acts as an unfavorable survival marker.

KIRC, SKCM, and UCEC are the cancer types where KRTAP25-1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	II,III,IV	0.127	0.806	<.001	108	view →
SKCM	OS	Tertile	All	0.233	0.787	.003	45	view →
UCEC	DFS	Tertile	IV	0.206	0.704	.033	18	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

KRTAP25-1–KIRC (OS)

Open the KIRC breakdown →