Across TCGA pan-cancer cohorts, KRTAP24-1 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated KRTAP24-1 data layer compared with 14 for mass-spec protein.
The strongest signal is observed in esophageal carcinoma (ESCA), where higher KRTAP24-1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated KRTAP24-1 expression acts as an unfavorable survival marker.
ESCA, LAML, and ACC are the cancer types where KRTAP24-1 Mutation most reproducibly stratifies survival.
Mutation survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.