Across TCGA pan-cancer cohorts, KRTAP20-3 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated KRTAP20-3 data layer compared with 9 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher KRTAP20-3 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated KRTAP20-3 expression acts as an unfavorable survival marker.

MESO and COAD are the cancer types where KRTAP20-3 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	III,IV	0.069	0.580	<.001	36	view →
COAD	OS	Median	All	0.168	0.806	.002	24	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: KRTAP20-3 tumor-vs-normal RNA expression · all KRTAP20-3 data types