KRTAP20-1

Across TCGA pan-cancer cohorts, KRTAP20-1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated KRTAP20-1 data layer compared with 8 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher KRTAP20-1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated KRTAP20-1 expression acts as an unfavorable survival marker.

HNSC, CESC, and ESCA are the cancer types where KRTAP20-1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	II,III,IV	0.086	0.743	<.001	30	view →
CESC	DFS	Median	All	0.070	0.823	<.001	12	view →
ESCA	DFS	Median	II,III,IV	0.089	0.522	.001	12	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

KRTAP20-1–HNSC (OS)

Open the HNSC breakdown →