KRTAP20-1

Across TCGA patient cohorts, KRTAP20-1 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible KRTAP20-1-associated genes across cancer lineages are HMGN2P26, SNORD115-32, and TRIM49D1. Each is linked with KRTAP20-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP20-1-to-partner and partner-to-KRTAP20-1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HMGN2P26 grouped by KRTAP20-1-low versus KRTAP20-1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP20-1→partner) and Y-score (partner→KRTAP20-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	HMGN2P26 →	+0.247	+5.516	<.001	.004	3	2
LUAD	SNORD115-32 →	+0.345	+7.930	<.001	.008	3	1
LUAD	TRIM49D1 →	+0.014	+7.930	<.001	.008	3	1
LUAD	DPP10-AS2 →	+0.054	+7.930	<.001	.008	3	1
LUAD	RNU6-1014P →	+0.280	+7.930	<.001	.008	3	1
LUAD	RNU1-48P →	+0.199	+7.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

HMGN2P26 by KRTAP20-1 expression — COAD

Explore this box plot interactively →