KRTAP2-5P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, KRTAP2-5P RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated KRTAP2-5P data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher KRTAP2-5P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KRTAP2-5P expression acts as an unfavorable survival marker, although some lineages such as READ show a favorable association.

THCA, STAD, and CESC are the cancer types where KRTAP2-5P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
THCAOSTertileAll0.7230.983<.00190view →
STADDFSTertileII,III,IV0.4450.711.00245view →
CESCOSTertileIV0.1210.591.02936view →
KIRPDFSTertileAll0.2180.771.02918view →
BLCAOSTertileIII,IV0.2050.475.0479view →
PCPGDFSTertileAll0.1610.819.0049view →
BRCAOSTertileII,III,IV0.9070.958.0486view →
READOSTertileIV1.0000.633.0436view →
UCECOSTertileAll0.8210.929.0286view →
Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

KRTAP2-5P–THCA (OS)

Kaplan–Meier survival curve for KRTAP2-5P RNA-high vs -low samples in THCA.

Open the THCA breakdown →

Exploration