Across TCGA cell cohorts, KRTAP2-4 RNA expression is significantly associated with the go_rna of many other GO terms, with 259 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KRTAP2-4-associated GO terms across cancer lineages are Positive regulation of purine nucleotide biosynthetic process, Regulation of extrinsic apoptotic signaling pathway via death domain receptors, and Positive regulation of ATP biosynthetic process. Each is linked with KRTAP2-4 in more than 3 cancer types. Because this analysis shows association rather than direction, both KRTAP2-4-to-partner and partner-to-KRTAP2-4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP2-4→partner) and Y-score (partner→KRTAP2-4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Positive regulation of purine nucleotide biosynthetic process →	+0.109	+0.080	.001	.009	3	4
LARGE_INTESTINE	Regulation of extrinsic apoptotic signaling pathway via death domain receptors →	+0.081	+0.147	.004	.009	3	4
LARGE_INTESTINE	Positive regulation of ATP biosynthetic process →	+0.108	+0.080	.001	.009	3	4
LARGE_INTESTINE	Positive regulation of nucleotide biosynthetic process →	+0.109	+0.080	.001	.009	3	4
LARGE_INTESTINE	Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors →	+0.087	+0.083	<.001	.006	3	3
LARGE_INTESTINE	Regulation of apoptotic signaling pathway →	+0.042	+0.082	.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 259 associations by consensus.

Exploration

KRTAP2-4 survival (RNA) · tumor vs normal (RNA) · all KRTAP2-4 data types