Across TCGA patient cohorts, KRTAP2-3 mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP2-3-associated genes across cancer lineages are SERF1A, RN7SL134P, and RN7SL498P. Each is linked with KRTAP2-3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP2-3-to-partner and partner-to-KRTAP2-3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP2-3→partner) and Y-score (partner→KRTAP2-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SERF1A →	+0.155	+3.476	<.001	.006	3	1
UCEC	RN7SL134P →	+0.280	+3.277	<.001	.002	3	1
UCEC	RN7SL498P →	+0.162	+3.133	.004	.009	3	1
UCEC	MIR4701 →	+0.848	+2.878	.009	.008	3	1
UCEC	PPIAP14 →	+0.511	+3.857	<.001	.002	3	1
UCEC	MIR5003 →	+0.368	+3.133	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Exploration

KRTAP2-3 survival (RNA) · tumor vs normal (RNA) · all KRTAP2-3 data types