Across TCGA pan-cancer cohorts, KRTAP19-5 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated KRTAP19-5 data layer compared with 14 for mass-spec protein.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher KRTAP19-5 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated KRTAP19-5 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

READ, LUAD, and UCEC are the cancer types where KRTAP19-5 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	DFS	Median	All	0.182	0.798	.010	9	view →
LUAD	DFS	Median	III,IV	0.036	0.673	<.001	6	view →
UCEC	DFS	Median	All	1.000	0.630	.039	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: KRTAP19-5 tumor-vs-normal RNA expression · all KRTAP19-5 data types