Across TCGA patient cohorts, KRTAP19-5 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP19-5-associated genes across cancer lineages are EGFR_pY1068, eIF4G, and Gab2. Each is linked with KRTAP19-5 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP19-5-to-partner and partner-to-KRTAP19-5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP19-5→partner) and Y-score (partner→KRTAP19-5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.350	-2.321	.005	.035	3	1
UCEC	eIF4G →	+0.351	+2.321	.024	.035	3	1
UCEC	Gab2 →	+0.404	+2.321	.024	.035	3	1
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.573	+3.009	.025	.019	3	1
UCEC	INPP4B →	-0.374	-2.308	.021	.036	3	1
UCEC	ACVRL1 →	-0.193	-2.986	.004	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

Exploration

KRTAP19-5 survival (RNA) · tumor vs normal (RNA) · all KRTAP19-5 data types