Across TCGA pan-cancer cohorts, KRTAP19-4 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated KRTAP19-4 data layer compared with 12 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher KRTAP19-4 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated KRTAP19-4 expression acts as an unfavorable survival marker.

COAD, UCEC, and SKCM are the cancer types where KRTAP19-4 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.096	0.806	<.001	36	view →
UCEC	OS	Median	III,IV	0.061	0.588	.018	18	view →
SKCM	DFS	Median	IV	0.040	0.454	.028	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: KRTAP19-4 tumor-vs-normal RNA expression · all KRTAP19-4 data types