Across TCGA pan-cancer cohorts, KRTAP19-1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated KRTAP19-1 data layer compared with 12 for mass-spec protein.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher KRTAP19-1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated KRTAP19-1 expression acts as an unfavorable survival marker.

CESC, COAD, and GBM are the cancer types where KRTAP19-1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Median	All	0.261	0.798	.006	12	view →
COAD	DFS	Median	II,III,IV	0.197	0.658	<.001	12	view →
GBM	DFS	Median	All	0.060	0.257	.005	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: KRTAP19-1 tumor-vs-normal RNA expression · all KRTAP19-1 data types