KRTAP17-1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KRTAP17-1 mutation is significantly associated with the RNA expression of many other genes, with 107 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible KRTAP17-1-associated genes across cancer lineages are TRAJ24, GFOD1-AS1, and CASTOR1. Each is linked with KRTAP17-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP17-1-to-partner and partner-to-KRTAP17-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP17-1→partner) and Y-score (partner→KRTAP17-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADTRAJ24 →+0.900+4.374<.001.00232
SKCMGFOD1-AS1 →+0.216+3.738.003.00131
SKCMCASTOR1 →+0.526+3.366.002.00531
SKCMZBTB20-AS2 →+0.037+4.640<.001.00331
SKCMLINC02016 →+0.043+2.592.006.00531
SKCMTRAJ60 →+0.342+3.290<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 107 associations by consensus.

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