KRTAP12-6P

Across TCGA pan-cancer cohorts, KRTAP12-6P RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated KRTAP12-6P data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher KRTAP12-6P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KRTAP12-6P expression acts as an unfavorable survival marker, although some lineages such as LUAD and PAAD show a favorable association.

BLCA, THCA, and OV are the cancer types where KRTAP12-6P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	All	0.152	0.722	<.001	108	view →
THCA	OS	Tertile	All	0.493	0.941	<.001	63	view →
OV	OS	Tertile	IV	0.272	0.765	.005	36	view →
READ	OS	Tertile	All	0.204	0.842	<.001	36	view →
HNSC	OS	Tertile	II,III,IV	0.466	0.748	.011	24	view →
LUAD	DFS	Tertile	II,III,IV	1.000	0.667	.024	18	view →
PAAD	OS	Tertile	All	1.000	0.373	.035	9	view →
COAD	OS	Tertile	All	0.733	0.875	.049	3	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

KRTAP12-6P–BLCA (OS)

Open the BLCA breakdown →