Across TCGA patient cohorts, KRTAP12-4 mutation is significantly associated with the RNA expression of many other genes, with 86 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible KRTAP12-4-associated genes across cancer lineages are RNU7-50P, SNORA30B, and MIR7702. Each is linked with KRTAP12-4 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP12-4-to-partner and partner-to-KRTAP12-4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP12-4→partner) and Y-score (partner→KRTAP12-4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU7-50P →	+0.740	+3.474	<.001	.006	3	2
SKCM	SNORA30B →	+0.123	+4.900	<.001	.002	3	2
UCEC	MIR7702 →	+0.537	+5.738	<.001	<.001	3	1
UCEC	MIR6763 →	+0.906	+3.663	.005	.007	3	1
SKCM	USH2A-AS1 →	+0.075	+2.978	<.001	.007	3	1
SKCM	SNORD13P3 →	+0.278	+2.915	.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 86 associations by consensus.

Exploration

KRTAP12-4 survival (RNA) · tumor vs normal (RNA) · all KRTAP12-4 data types