Across TCGA pan-cancer cohorts, KRTAP10-8 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated KRTAP10-8 data layer compared with 8 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher KRTAP10-8 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated KRTAP10-8 expression acts as an unfavorable survival marker.

ACC, HNSC, and LUSC are the cancer types where KRTAP10-8 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	All	0.118	0.624	.038	6	view →
HNSC	OS	Median	All	0.151	0.685	.007	6	view →
LUSC	DFS	Median	All	0.248	0.750	.003	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: KRTAP10-8 tumor-vs-normal RNA expression · all KRTAP10-8 data types