KRTAP10-7

Across TCGA cell cohorts, KRTAP10-7 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible KRTAP10-7-associated genes across cancer lineages are RESP18, KRTAP20-2, and PNMA6F. Each is linked with KRTAP10-7 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP10-7-to-partner and partner-to-KRTAP10-7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RESP18 grouped by KRTAP10-7-low versus KRTAP10-7-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP10-7→partner) and Y-score (partner→KRTAP10-7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	RESP18 →	+0.045	+5.196	<.001	.005	3	1
OVARY	KRTAP20-2 →	+0.117	+5.196	<.001	.005	3	1
LUNG_NSCLC_LUAD	PNMA6F →	+0.006	+4.887	.009	.009	3	1
LUNG_NSCLC_LUAD	DBX2 →	+0.026	+4.857	<.001	.009	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

RESP18 by KRTAP10-7 expression — OVARY

Explore this box plot interactively →