KRTAP10-5

Across TCGA pan-cancer cohorts, KRTAP10-5 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated KRTAP10-5 data layer compared with 9 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher KRTAP10-5 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated KRTAP10-5 expression acts as an unfavorable survival marker.

SKCM and UCEC are the cancer types where KRTAP10-5 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	III,IV	0.216	0.721	.001	9	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

KRTAP10-5–SKCM (OS)

Open the SKCM breakdown →