Across TCGA patient cohorts, KRTAP10-12 mutation is significantly associated with the RNA expression of many other genes, with 493 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP10-12-associated genes across cancer lineages are CCDC105, RNU6-13P, and AKR1B10P2. Each is linked with KRTAP10-12 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP10-12-to-partner and partner-to-KRTAP10-12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP10-12→partner) and Y-score (partner→KRTAP10-12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCDC105 →	+0.357	+1.988	<.001	.009	3	2
COAD	RNU6-13P →	+0.522	+5.893	<.001	.002	3	2
UCEC	AKR1B10P2 →	+0.043	+3.037	<.001	.002	3	2
SKCM	CYCSP53 →	+0.138	+4.771	<.001	.006	3	2
UCEC	RNU6-380P →	+0.144	+3.885	<.001	.008	3	2
UCEC	RN7SKP286 →	+0.061	+4.475	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 493 associations by consensus.

Exploration

KRTAP10-12 survival (RNA) · tumor vs normal (RNA) · all KRTAP10-12 data types