Across TCGA cell cohorts, KRTAP10-12 mutation is significantly associated with the mutation status of many other genes, with 241 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KRTAP10-12-associated genes across cancer lineages are SEMA3F, CX3CL1, and ZNF691. Each is linked with KRTAP10-12 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP10-12-to-partner and partner-to-KRTAP10-12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP10-12→partner) and Y-score (partner→KRTAP10-12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SEMA3F →	+4.000	+5.050	.008	.008	1	2
BLOOD_Leukemia	CX3CL1 →	+4.000	+5.050	.008	.008	1	2
BLOOD_Leukemia	ZNF691 →	+4.736	+5.560	.003	.003	1	2
BLOOD_Leukemia	EIF3C →	+4.321	+5.285	.005	.005	1	2
LUNG_SCLC	IFNL3 →	+4.502	+5.066	.007	.007	1	2
BLOOD_Lymphoma	ADCYAP1R1 →	+4.014	+4.969	.008	.008	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 241 associations by consensus.

Exploration

KRTAP10-12 survival (RNA) · tumor vs normal (RNA) · all KRTAP10-12 data types