KRTAP10-11

Across TCGA pan-cancer cohorts, KRTAP10-11 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated KRTAP10-11 data layer compared with 3 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher KRTAP10-11 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KRTAP10-11 expression acts as an unfavorable survival marker, although some lineages such as COAD and SCLC show a favorable association.

UCEC, SKCM, and OV are the cancer types where KRTAP10-11 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	III,IV	0.720	0.851	.015	78	view →
SKCM	DFS	Tertile	All	0.348	0.628	<.001	66	view →
OV	OS	Tertile	II,III,IV	0.185	0.330	.006	36	view →
BLCA	DFS	Tertile	All	0.173	0.602	.003	27	view →
ACC	OS	Tertile	IV	0.327	0.633	.045	24	view →
LGG	DFS	Tertile	All	0.152	0.411	.004	18	view →
KIRC	DFS	Tertile	All	0.447	0.670	.015	14	view →
COAD	DFS	Tertile	III,IV	0.832	0.384	.026	12	view →
PCPG	DFS	Tertile	All	0.603	0.903	.014	9	view →
SCLC	OS	Quartile	All	0.796	0.577	.027	4	view →
KICH	OS	Tertile	All	0.809	0.936	.047	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

KRTAP10-11–UCEC (OS)

Open the UCEC breakdown →